“Higher nicotine concentration in vape juice equals better quitting rate”

HIGHER concentrations of nicotine in vape e-liquids are likely to lead to higher quit rates among smokers, according to a new study from the US.

The study led by scientist Nicholas I. Goldenson compared switching rates in the North America (US and Canada) and the UK which has more restrictive regulations.

In the UK, the nicotine concentration in vape e-liquids is limited to 20mg/ml compared to North America, where higher concentrations of 59mg/ml and 35mg/ml are available.

In the study, published in the Nicotine and Tobacco Research journal, the research team compared switching rates at one, three and six months after purchase.

The researchers found that switch rates were significantly greater in North America with odds of switching being 24% to 63% higher among North America smokers compared to their UK counterparts.

“These results suggest availability of electronic nicotine delivery systems (ENDS) in nicotine concentrations greater than 20 mg/ml may be associated with increased switching among adult smokers,” the study pointed out.

“Conceptually, switching is expected to be facilitated when ENDS provide adequate nicotine delivery as dose–response effects are fundamental to pharmacological action of nicotine.”

The study noted that in the context of nicotine replacement, randomised clinical trials also show that nicotine gum with higher doses is more effective in heavier and more dependent smokers.

The study’s findings provide valuable insights for regulators and policymakers in Malaysia, where industry players and health experts have long called for regulation of vaping that is different from traditional cigarettes.

This was reflected in a recent survey of over 1,000 vape users in the country by the Malaysian Vapers Alliance (MVA), a local vape consumer advocacy group.

The survey found that 79% of vape users would use vape e-liquids containing 40mg to 50mg nicotine. Some 85% of vape users said if regulations cap nicotine levels lower than the 40mg to 50mg, they will opt for unregulated vape e-liquids.

Such a situation, would lead to the creation of a black market for vape products, exposing consumers to products that are not manufactured according to safety and quality guidelines. — March 6, 2022

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